Saffron used for the treatment of liver cancer

As indicated by researchers and students at the United Arab Emirates University, the treatment of liver malignant growth through the spice of saffron has been turned out to be successful.

Ameera AlMansoori, a 25-year-old Emirati who has graduated with a Masters in sub-atomic science and biotechnology, concentrated on the point through her exploration venture, state news organization WAM revealed.

It said, After cancer was initiated in rodents, they were administered an oral gavage of safranal substance, which is a bioactive particle of saffron. Tests directed on the liver and blood uncovered profoundly powerful outcomes in treating cancer.

She said, “When you work with animals, it is more reliable than cells.”

She added, “It is the whole organism and not just cells. Dr Amr Amin, professor of cellular and molecular biology at the university, works with liver cancer and saffron, so I continued his project.”

She also said, “This is something new, and working with animals is a huge step.”

She included, “Cancer is also spreading a lot now so we need to find a solution for it.”

The rodents were given an injection of a chemical – DEN – which causes malignant growth once every week for 15 weeks and disease was found in the liver.

The medication was then given to the animals for three straight weeks and various promising outcomes from the blood were found – enzymes that acted as markers for liver harm.

The drug was then given to the animals for three straight weeks and a number of promising results from the blood were discovered – enzymes that acted as markers for liver damage.

She noted, “Firstly, safranal reduced these markers.”

She also noted “Secondly, we did tests on the liver itself and tested some proteins. Safranal suppressed the cell cycle and induced cell death (apoptosis).”

She told “We still need to do more tests because I have just tested two pathways of many. Usually, cancer has 11 hallmarks, and also, we hopefully want this to be used on humans someday because the drug comes from a natural source, saffron, which has no side effects as compared to chemotherapy.”

She further said, “I think it could be used on humans soon. In 2016, liver cancer was the fourth cause of death related to cancer in the UAE.”

AlMansoori said she is seeking chances to distribute her experiments before leaving the college towards the completion of the semester, with the expectations of proceeding with her work in cancer research at the Khalifa Hospital given the presence of laboratories in the field.

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